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Power, Sex, Suicide
- Mitochondria and the Meaning of Life
- Narrated by: Nigel Patterson
- Length: 15 hrs and 54 mins
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Publisher's summary
Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that.
Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to "Mitochondrial Eve".
Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide.
In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to reveal how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death.
Critic reviews
"Full of startling insights into the nature and evolution of life as we know it." (The Economist)
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The cells in our bodies consist of molecules, made up of the same carbon, oxygen, and hydrogen atoms found in air and rocks. But molecules, such as water and sugar, are not alive. So how do our cells - assemblies of otherwise "dead" molecules - come to life, and together constitute a living being? In Life’s Ratchet, physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale.
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For biologists to learn single molecule biophysics
- By A Synthetic Biologist on 09-04-14
By: Peter M. Hoffman
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Welcome to the Microbiome
- Getting to Know the Trillions of Bacteria and Other Microbes In, On, and Around You
- By: Rob DeSalle, Susan L. Perkins
- Narrated by: Stephen McLaughlin
- Length: 7 hrs and 25 mins
- Unabridged
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Suddenly, research findings require a paradigm shift in our view of the microbial world. The Human Microbiome Project at the National Institutes of Health is well under way, and unprecedented scientific technology now allows the censusing of trillions of microbes inside and on our bodies as well as in the places where we live, work, and play. This intriguing, up-to-the-minute book for scientists and nonscientists alike explains what researchers are discovering about the microbe world and what the implications are for modern science and medicine.
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I learned so much from this book. I am happy.
- By Jonathan Miller on 09-08-18
By: Rob DeSalle, and others
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A Series of Fortunate Events
- Chance and the Making of the Planet, Life, and You
- By: Sean B. Carroll
- Narrated by: Sean B. Carroll
- Length: 4 hrs and 48 mins
- Unabridged
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Why is the world the way it is? How did we get here? Does everything happen for a reason, or are some things left to chance? Philosophers and theologians have pondered these questions for millennia, but startling scientific discoveries over the past half century are revealing that we live in a world driven by chance. A Series of Fortunate Events tells the story of the awesome power of chance and how it is the surprising source of all the beauty and diversity in the living world.
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We are for a short time.
- By Anonymous User on 10-14-20
By: Sean B. Carroll
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What Is Life?
- How Chemistry Becomes Biology
- By: Addy Pross
- Narrated by: Derek Perkins
- Length: 6 hrs and 50 mins
- Unabridged
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Seventy years ago, Erwin Schrdinger posed a simple, yet profound, question: What is life?. How could the very existence of such extraordinary chemical systems be understood? This problem has puzzled biologists and physical scientists both before, and ever since. Living things are hugely complex and have unique properties, such as self-maintenance and apparently purposeful behaviour which we do not see in inert matter. So how does chemistry give rise to biology?
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Profound & Life Changing...
- By Daegan Smith on 04-06-15
By: Addy Pross
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The Blind Watchmaker
- Why the Evidence of Evolution Reveals a Universe Without Design
- By: Richard Dawkins
- Narrated by: Richard Dawkins, Lalla Ward
- Length: 14 hrs and 40 mins
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The Blind Watchmaker, knowledgably narrated by author Richard Dawkins, is as prescient and timely a book as ever. The watchmaker belongs to the 18th-century theologian William Paley, who argued that just as a watch is too complicated and functional to have sprung into existence by accident, so too must all living things, with their far greater complexity, be purposefully designed. Charles Darwin's brilliant discovery challenged the creationist arguments; but only Richard Dawkins could have written this elegant riposte.
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Challenging textbook more than an enjoyable listen
- By Eric on 01-15-12
By: Richard Dawkins
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Human Errors
- A Panorama of Our Glitches, from Pointless Bones to Broken Genes
- By: Nathan H. Lents
- Narrated by: L.J. Ganser
- Length: 7 hrs and 54 mins
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We humans like to think of ourselves as highly evolved creatures. But if we are supposedly evolution's greatest creation, why do we have such bad knees? Why do we catch head colds so often - 200 times more often than a dog does? How come our wrists have so many useless bones? And are we really supposed to swallow and breathe through the same narrow tube? Surely there's been some kind of mistake. As professor of biology Nathan H. Lents explains in Human Errors, our evolutionary history is nothing if not a litany of mistakes, each more entertaining and enlightening than the last.
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From Pointless Bones to Broken Genes to...Aliens?
- By Katy.LED on 12-04-18
By: Nathan H. Lents
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Life on the Edge
- The Coming of Age of Quantum Biology
- By: Johnjoe McFadden, Jim Al-Khalili
- Narrated by: Pete Cross
- Length: 12 hrs and 40 mins
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Life is the most extraordinary phenomenon in the known universe; but how did it come to be? Even in an age of cloning and artificial biology, the remarkable truth remains: Nobody has ever made anything living entirely out of dead material. Life remains the only way to make life. Are we still missing a vital ingredient in its creation?
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More woo than new
- By Gary on 09-09-15
By: Johnjoe McFadden, and others
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Pandora's Seed
- The Unforeseen Cost of Civilization
- By: Spencer Wells
- Narrated by: Spencer Wells
- Length: 6 hrs and 40 mins
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This new book by Spencer Wells, the internationally known geneticist, anthropologist, author, and director of the Genographic Project, focuses on the seminal event in human history: mankind's decision to become farmers rather than hunter-gatherers.
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Short and unfocused, but often quite interesting.
- By Alan on 06-23-10
By: Spencer Wells
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At the Edge of Uncertainty
- 11 Discoveries Taking Science by Surprise
- By: Michael Brooks
- Narrated by: Sean Runnette
- Length: 9 hrs and 12 mins
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The atom, the big bang, DNA, natural selection - all are ideas that have revolutionized science; and all were dismissed out of hand when they first appeared. The surprises haven't stopped in recent years, and in At the Edge of Uncertainty, best-selling author Michael Brooks investigates the new wave of radical insights that are shaping the future of scientific discovery.
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All smoke, no fire
- By Kenton on 07-25-15
By: Michael Brooks
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How to Build a Dinosaur
- Extinction Doesn't Have to Be Forever
- By: Jack Horner, James Gorman
- Narrated by: Patrick Lawlor
- Length: 6 hrs and 36 mins
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In movies, in novels, in comic strips, and on television, we've all seen dinosaurs - or at least somebody's educated guess of what they would look like. But what if it were possible to build, or grow, a real dinosaur without finding ancient DNA? Jack Horner, the scientist who advised Steven Spielberg on the blockbuster film Jurassic Park and a pioneer in bringing paleontology into the 21st century, teams up with the editor of the New York Times's Science Times section to reveal exactly what's in store.
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Good book but misplaced title
- By Robert on 06-19-15
By: Jack Horner, and others
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Evolving Ourselves
- How Unnatural Selection and Nonrandom Mutation are Changing Life on Earth
- By: Juan Enriquez, Steve Gullans
- Narrated by: Rob Shapiro
- Length: 10 hrs and 50 mins
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Why are conditions like autism, asthma, obesity, and allergies exploding at unprecedented rates? Why are we living longer, getting smarter, having far fewer kids? If Darwin were alive today, how would he explain this new world?
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fascinating ideas and science
- By Joel on 07-04-15
By: Juan Enriquez, and others
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Average customer ratingsReviews - Please select the tabs below to change the source of reviews.
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- Debra M. Givin
- 01-09-22
Great Title …
You will need at least a basic knowledge of biology to really enjoy this book. It is worth the effort if you would like to acquire a different perspective on life and where human kind perhaps all multicellular earthlings may fit in the scheme of things.
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- Anil K S Nair
- 10-30-19
best ever book in science that everyone shud read
loved it. one of the best books in molecular science, origin of life that explains so many secrets of life on this Earth.
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1 person found this helpful
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- LiveMind
- 10-08-23
An outstanding science book
This book is an eye opener. As an MD, and a pathologist I was of course familiar with mitochondria in their basic role as the cell's power houses. The relationships Lane describes between mitochondria and the aging process are an eye opener into a completely new field. This book is not a recapitulation of known facts for the general public, but a vigorous new thesis worthy of the most careful consideration and exploration.
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- saltinbas
- 09-13-20
One of the best books about origins of life
Aftet reading couple of books about evolutionary biology, I can easily say that this book is one of the best.
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- sam
- 05-03-20
Nick Lane as usual
Mitochondria explain a lot, if you are interested in understanding the very basics of life read this book
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- GCG
- 06-12-19
Nick Lane Continues to ask the Vital Questions
If your looking to increase your understanding of what present science can tells us about the origins and nature of being alive - this book is an excellent place to begin and journeys a long way down the road.
Nick Lane does a wonderful job of bringing the reader along, on his search to understand cellular biology and complex eukaryotic life. He accomplishes this by providing the reader the pertinent history relative to our twisting path of understanding using the mitochondria's pivotal influence as our guide.
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3 people found this helpful
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- Kristian E Stubkjaer
- 12-04-23
complet topic
enjoyed listening - but ned to hear again to comprehend. No doubt the topic is important
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- Brad Ford
- 11-23-22
Wonderful book!
Love learning about mitochondria and the science being aging and dysfunction and the mechanisms that drive them :)
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1 person found this helpful
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- MR
- 10-23-23
Powerful
As a non-science person there were parts that challenges my comprehension but the majority was fascinating and illuminating. I wonder where these insights will take us.
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- Amazon Customer
- 03-25-19
YES A Nick Lane Book!
Keep them coming please. I live in Canada and I can’t purchase Nick Lane’s other books like Life Ascending and Oxygen. I WANT THEM ALL!!
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5 people found this helpful